August 7, 2023

 

Via EDGAR

 

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attn:       Jessica Ansart

 

Re:	Yield10 Bioscience, Inc. (the “Company”)
	Registration Statement Filed on Form S-1, as amended (the “Registration Statement”)
	File No. 333-273240

 

Ladies and Gentlemen:

 

Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company hereby respectfully requests that the effective date for the above-referenced Registration Statement be accelerated to 5:00 p.m., Eastern Time, on August 9, 2023, or as soon as practicable thereafter.

 

Please contact Megan Gates of Covington & Burling LLP at (617) 603-8805 or mgates@cov.com with any questions you may have regarding this request. In addition, please notify Ms. Gates by telephone when this request for acceleration has been granted.

 

		Respectfully,
		Yield10 Bioscience, Inc.
	By:	/s/ Oliver P. Peoples
	Name:	Oliver P. Peoples
	Title:	President & Chief Executive Officer

 

cc: Megan Gates, Covington & Burling LLP