DocumentYield10 Bioscience, Inc.
19 Presidential Way
Woburn, Massachusetts 01801
March 31, 2021
VIA EDGAR
U.S. Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
Attention: Charles Eastman, Staff Accountant
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| | Re: | | Yield10 Bioscience, Inc. |
| | | | Registration Statement on Form S-3 |
| | | | File No. 333-254830 |
| | | | Request for Acceleration |
Dear Mr. Eastman:
Pursuant to Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, Yield10 Bioscience, Inc. (the “Registrant”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-254830), so that it may become effective at 12:00 p.m. (Washington, D.C. time) on April 2, 2021, or as soon thereafter as practicable.
Please call Megan Gates, of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., counsel to the Registrant, at (617) 348-4443 with any comments or questions regarding this matter.
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| Very truly yours, Yield10 Bioscience, Inc. | |
| By: | /s/ Charles B. Haaser | |
| | Name: | Charles B. Haaser | |
| | Title: | Vice President, Finance, Chief Accounting Officer and Treasurer | |
cc: Yield10 Bioscience, Inc.
Oliver P. Peoples, Ph.D.
Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
Megan N. Gates, Esq.