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SEC FORM 4 SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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OMB Number:			3235-0287
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Muller Edward M

(Last)

(First)

(Middle)

C/O METABOLIX, INC.

21 ERIE STREET

(Street)

CAMBRIDGE

02139

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
METABOLIX, INC. [ MBLX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	10% Owner
	Officer (give title below)	Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
03/03/2008

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	03/03/2008		S⁽¹⁾		15,000	D	$15.4999⁽²⁾	930,091	D
Common Stock								23,376	I	By The Lara Muller Irrevocable Trust 2000⁽³⁾

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:

1. Transaction effected pursuant to a Rule 10b5-1 trading plan established by the reporting person on 3/16/07.

2. Price reflected is the average sale price for the shares sold. Please see attached Exhibit 99 for a complete list of all sales by sale price.

3. Held by a trust for the benefit of family members. The reporting person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any. The reporting person no longer has a reportable beneficial interest in shares of Metabolix common stock held by the Gwyneth Muller Irrevocable Trust 2000 and included in the reporting person's prior ownership reports.

	/s/ Sarah P. Cecil, attorney-in-fact	03/04/2008
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

Exhibit 99 filed on behalf of Edward M. Muller for Transaction date 3/3/08
Price 	       Share
$ 15.9800 	500
$ 15.9500 	800
$ 15.9400 	294
$ 15.9300 	106
$ 15.9200 	100
$ 15.9100 	800
$ 15.9000 	200
$ 15.8900 	100
$ 15.8800 	500
$ 15.8700 	300
$ 15.8600 	200
$ 15.8500 	300
$ 15.8200 	200
$ 15.8000 	100
$ 15.7800 	235
$ 15.7600 	165
$ 15.7500 	400
$ 15.6800 	100
$ 15.6700 	100
$ 15.6600 	200
$ 15.6500 	200
$ 15.6000 	200
$ 15.5800 	600
$ 15.5700 	800
$ 15.5600 	100
$ 15.5500 	200
$ 15.5400 	100
$ 15.5200 	100
$ 15.5000 	100
$ 15.4500 	100
$ 15.3600 	300
$ 15.3500 	300
$ 15.3300 	100
$ 15.3000 	 99
$ 15.2700 	200
$ 15.2600 	100
$15.2500 	300
$15.2400 	400
$15.2300       1600
$15.2200 	100
$15.2000 	300
$15.1800 	100
$15.1700 	200
$15.1500 	100
$15.1300 	100
$15.1100 	200
$15.1000 	100
$15.0700 	100
$15.0500 	100
$15.0300 	300
$15.0200 	401
$15.0100 	600
$15.0000 	600
$14.9200 	100