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SEC FORM 3 SEC Form 3
FORM 3 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940 		 
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1. Name and Address of Reporting Person*
Barber James J
(Last) (First) (Middle)
C/O METABOLIX, INC.
21 ERIE STREET
(Street)
CAMBRIDGE MA 02139
(City) (State) (Zip)
2. Date of Event Requiring Statement (Month/Day/Year)
11/09/2006 		3. Issuer Name and Ticker or Trading Symbol
METABOLIX, INC. [ MBLX ]
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
President and CEO
5. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock 13,342 D
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year) 3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) (1) 01/22/2010 Common Stock 178,723 3.3 D
Stock Option (right to buy) (1) 01/22/2010 Common Stock 47,403 13.21 D
Stock Option (right to buy) (2) 12/14/2015 Common Stock 198,795 1.84 D
Stock Option (right to buy) (3) 12/14/2015 Common Stock 41,954 1.84 D
Stock Option (right to buy) (4) 12/14/2015 Common Stock 41,955 1.84 D
Explanation of Responses:
1. This option is fully vested and exercisable.
2. This option was vested as to 35,961 shares immediately upon grant. The remainder vests at the rate of 6.25% per quarter from 1/1/05.
3. This option vests as to 50% of the shares upon completion of the Issuer's initial public offering. The remainder will vest at the rate of 6.25% per quarter from 1/1/05.
4. This option vested as to 50% of the shares on 7/12/06. The remainder vests at the rate of 6.25% per quarter from 1/1/05.
Remarks:
Exhibit 24 - Power of Attorney
/s/ Sarah P. Cecil, attorney-in-fact 11/09/2006
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
Exhibit 24

POWER OF ATTORNEY

	KNOW ALL MEN BY THESE PRESENTS, that the
undersigned hereby constitutes and appoints Thomas G.
Auchincloss, Jr., Aninda Katragadda, Sarah Cecil,
Christopher J. Denn, John M. Mutkoski, and Robert E.
Puopolo, and any one of them acting singly, the true
and lawful attorneys-in-fact and agents, with full
power of substitution and resubstitution, for the
undersigned and in the undersigned's name, place and
stead, in any and all capacities (until revoked in
writing) to execute for and on behalf of the
undersigned, in any and all of the undersigned's
capacities, any and all statements on Forms 3, 4 and 5
with respect to the undersigned's holdings of and
transactions in securities issued by Metabolix, Inc.
(the "Company") in accordance with Sections 16(a) of
the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), and any and all regulations
promulgated thereunder, and to file the same, with all
exhibits thereto, and any other documents in
connection therewith, with the Securities and Exchange
Commission, and with any other entity when and if such
is mandated by the Exchange Act or by the By-laws of
the National Association of Securities Dealers,
granting unto said attorneys-in-fact and agents full
power and authority to do and perform each and every
act and thing requisite and necessary fully to all
intents and purposes as the undersigned might or could
do in person thereby ratifying and confirming all that
said attorneys-in-fact and agents, or their substitute
or substitutes, may lawfully do or cause to be done by
virtue hereof.

	This Power of Attorney shall remain in full force
and effect until the undersigned is no longer required
to file Forms 3, 4 and 5 with respect to the
undersigned's holdings of and transactions in
securities issued by the Company, unless earlier
revoked by the undersigned in a signed writing
delivered to the foregoing attorneys-in-fact.

	IN WITNESS WHEREOF, this Power of Attorney has
been signed as of November 5, 2006.


Signature:	/s/ James J. Barber

Name:  James J. Barber