Document and Entity Information - USD ($)
12 Months Ended
Dec. 31, 2017
Jun. 30, 2017
Document and Entity Information    
Entity Registrant Name YIELD10 BIOSCIENCE, INC.  
Entity Central Index Key 0001121702  
Current Fiscal Year End Date --12-31  
Entity Filer Category Smaller Reporting Company  
Document Type 10-K  
Document Period End Date Dec. 31, 2017  
Document Fiscal Year Focus 2017  
Document Fiscal Period Focus FY  
Amendment Flag false  
Entity Common Stock, Shares Outstanding 28,402,471  
Entity Well-known Seasoned Issuer No  
Entity Voluntary Filers No  
Entity Current Reporting Status Yes  
Entity Public Float   $ 7,869,303